Autonomic nervous system

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Autonomic nervous system

A simplified medical illustration of the central nervous system (brain and spinal cord) in the center, flanked by red arrows pointing left representing the sympathetic system and green arrows pointing right representing the parasympathetic system. The text "ANS" is at the top and "CNS" is at the bottom against a light blue background.The autonomic nervous system controls involuntary actions in the body like heart rate, blood pressure, digestion, and more.

In ME/CFS, it is widely accepted that the autonomic nervous system doesn’t function correctly, which is called dysautonomia. This contributes to some of the major symptoms of ME/CFS, including fatigue.

OMF’s clinical trial, the Life Improvement Trial (LIFT), is investigating two drugs: pyridostigmine and low-dose naltrexone. Pyridostigmine has been used off-label to manage dysautonomia, so the LIFT may, in part, help to address dysautonomia in ME/CFS. Read more about the trial on our website: https://www.omf.ngo/the-life-improvement-trial/

A simplified medical illustration of the central nervous system (brain and spinal cord) in the center, flanked by red arrows pointing left representing the sympathetic system and green arrows pointing right representing the parasympathetic system. The text "ANS" is at the top and "CNS" is at the bottom against a light blue background.
Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation®

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